The OPA378 and OPA2378 represent a new generation of Zer-Drift, microPOWERTM operational amplifiers that use a proprietary auto-calibration technique to provide minimal input offset voltage (50V max) and offset voltage drift (0.25V/C max). The combination of low input voltage noise, high gain bandwidth (900kHz), and low power (150A max) enable these devices to achieve optimum performance for low-power precision applications. In addition, the excellent PSRR performance, coupled with a wide input supply range of 2.2V to 5.5V and rail-to-rail input and output, makes it an outstanding choice for single-supply applications that run directly from batteries without regulation.