The LMP8645 and the LMP8645HV are precision current sense amplifiers that detect small differential voltages across a sense resistor in the presence of high input common mode voltages with a supply voltage range from 2.7V to 12V. The LMP8645 accepts input signals with common mode voltage range from -2V to 42V, while the LMP8645HV accepts input signal with common mode voltage range from -2V to 76V. The LMP8645 and LMP8645HV have adjustable gain for applications where supply current and high common mode voltage are the determining factors. The gain is configured with a single resistor, providing a high level of flexibility, the accuracy could be as low as 2% (max) including the gain setting resistor. The output is buffered in order to provide low output impedance. This high side current sense amplifier is ideal for sensing and monitoring currents in DC or battery powered systems, excellent AC and DC specifications over temperature, and keeps errors in the current sense loop to a minimum. The LMP8645 is an ideal choice for industrial, automotive and consumer applications, and it is available in TSOT-6 package.