The ADC12048's 8-channel multiplexer is software programmable to operate in a variety of combinations of single-ended, differential, or pseudo-differential modes. The fully differential MUX and the 12-bit + sign ADC allows for the difference between two signals to be digitized. The ADC12048 can be configured to work with many popular microprocessors/microcontrollers and DSPs including National's HPC family, Intel386 and 8051, TMS320C25, Motorola MC68HC11/16, Hitachi 64180 and Analog Devices ADSP21xx.