The OP250 and OP450 are dual and quad CMOS single-supply, amplifiers featuring rail-to-rail inputs and outputs. Both are guaranteed to operate from a +2.7 V to +5 V single supply. These amplifiers have very low input bias currents. Outputs are capable of driving 100 mA loads and are stable with capacitive loads. Supply current is less than 1 mA per amplifier. Applications for these amplifiers include portable medical equipment, safety and security, and interface to transducers with high output impedance.