The AD8251 is a digitally gain programmable instrumentation amplifier that has high G input impedance and low distortion making it suitable for sensor interfacing and driving high sample rate analog to digital converters. It has high bandwidth of 12MHz, low distortion and settle time of 0.5us to 0.01%. Offset drift and gain drift are limited to 1uV/C and 10ppm/C respectively. In addition to its wide input common-voltage range, it boasts a high common-mode rejection of 80dB at G=1 from DC to 50kHz. The combination of precision DC performance coupled with high speed capabilities make the AD8251 an excellent candidate for data acquisition and medical applications. Furthermore, this monolithic solution simplifies design, manufacturing and boosts performance of instrumentation by maintaining tight match of internal resistors and amplifiers.