The AD8209 is a single-supply difference amplifier ideal for amplifying and low-pass filtering small differential voltages in the presence of a large common-mode voltage. The input commonmode voltage range extends from -2 V to +45 V at a single +5 V supply. The AD8209 is qualified per AEC-Q100 specifications. The amplifier offers enhanced input overvoltage and ESD protection, and includes EMI filtering.